Latest T-cell therapy of cancer in clinical trials in the Israeli Sheba hospital
In Israel's largest hospital. Chaim Sheba (tel Hashomer), the national Institute for prevention, treatment and research of cancer. For this no matter the nationality of the patient – here are advanced therapy of various cancer diseases, people from all over the world. Sheba medical center is constantly striving to improve the treatment of cancer using the latest robotic and computerized equipment, as well as developing innovative, more effective and safe methods.
Along with the use of standard technologies in the fight against malignant tumors, Israeli doctors hospital participating in international clinical research and development of advanced approaches to improve the lives of their patients. To achieve these goals, the Sheba hospital has a special unit that works closely with the world's research laboratories. A team of leading specialists of the clinic develops new ways of dealing with cancer, one of which is therapy using chimeric antigen receptor (Chimeric antigen receptor – CAR) T-cells.
Innovative cancer treatment with the help of genetic engineering at Sheba hospital
the Cancer has the ability to suppress the immune system or to evade it. For example, the malignancy can disable T-cell immune response, thereby contributing to the survival and development of cancer tissues. In response, researchers and doctors are exploring immunotherapeutic approaches that enhance antitumor immunity Arsenal. One of the new strategies of treatment which shows significant promise is CAR T-cell therapy. T cells represent a powerful tool aimed at the destruction of cancer cells. Itself antigen receptor (CAR) provides a strong bond between the antibody and the signal plot of T-cells. First, T cells are removed from a patient for the expression of the CAR, after which they returned to the body to more effectively fight the tumor.
This innovative method of cancer treatment in the framework of personalized medicine has many advantages:
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the
- T-cells change under the careful supervision of researchers in the lab; the
- as the patient receives their own T cells, rejection of tissue is excluded; the
- modified CAR T-cells may continue to grow and function, preventing tumor recurrence; the
- technology for creating molecules CAR continues to improve.
the Main progress of the application of T-cell therapy in clinical trials at Sheba hospital is a significant regression of leukemia and lymphoma. Today this method is used to treat breast cancer and colon cancer.
for decades clinics are world leaders in innovative treatment of all types of cancer. In the Sheba hospital every year come to pass advanced tests and treatment, thousands of tourists from all over the world, receiving medical care at the highest level at a better price than in the developed countries of Europe and America.
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Source: http://uzinform.com.ua/