Prevention of vascular disorders in diabetic patients using dietary supplements ART LIFE.
AA VEKOVTSEV, IL Kaverina, NGO ART LIFE, Tomsk
In the structure of endocrine diseases diabetes mellitus (DM) up to 70% of cases. Characteristic of him are hyperglycaemia and disorders of all kinds of metabolism due to absolute or relative deficiency of insulin. In diabetes mellitus in first place on the frequency of lesions is the cardiovascular system. It happens so often that many researchers have called DM exchange-vascular diseases. In DM risk of death from myocardial infarction or other vascular accident is 4-5 times higher than that in the absence of diabetes. Frequent and serious complication of diabetes are also oklyuzionnye vascular limbs, which usually leads to the development of gangrene and amputation, which in turn causes the growth of early disability of patients and deaths. Statistical studies show that over 50% of all lower limb amputations due to diabetes.
When there are two types of diabetes vascular lesion: large - macroangiopathy and small - microangiopathy. Changes in small blood vessels in DM is strictly specific and characterized by thickening and splitting of the basement membrane of capillaries, venules, arteries, deposition in her gialinopodobnyh substances, fats, proteins, increased permeability of the vascular wall. These changes are explained by disturbances in the metabolism of proteins, fats and carbohydrates, resulting from insulin deficiency, and a violation of its metabolism in tissues. The most severe clinical manifestations of diabetes develops in the presence of microangiopathy in the retina and kidney.
Diabetic retinopathy in 2% of patients leads to complete blindness. Vascular lesions of kidneys in turn leads to the development of nephropathy and subsequent renal failure. Macroangiopathy is mainly characterized by atherosclerosis, due to impaired lipid metabolism.
During chronic diabetes and tends to progress, but we know that good diabetes compensation in light of its forms is possible to achieve long-term remission, while moderate forms can be transformed into light and heavy forms - a moderate. In the absence of compensation for the disease tends to worsen.
With this in mind, there is no doubt that, to prevent severe complications of diabetes and stabilization of the disease, patients should receive adequate systemic therapy aimed at improving the microcirculation in the tissues and the stabilization of metabolic processes in them. It is very important to maintain a normal level of activity indicators of the blood coagulation system. Therapeutic measures for diabetes are sufficiently developed and must include diet, hypoglycemic agents (oral or by injection), the means of symptomatic therapy.
Along with medication, phytotherapeutic means having a mild and versatile effect, can be successfully used in conjunction with diet as a base therapy in the treatment of patients with latent or mild form of diabetes. For the treatment of patients with diabetes secondary to severe disease herbs can be used as aids to the calculation of the possible lower dosages of medicines, providing a more long-term remission, prevention of complications.
In the hospitals he. Tomsk and Voronezh have been studied biologically active food additives (BAA) MEMORY RISE (production company ARTLIFE ) for the prevention and treatment of diabetic angiopathies, including diabetic foot. Number of observations was 23 patients of different age and sex with different forms and severity of diabetes.
MEMORYRISE is a complex product in an easy to use tablet form that is based on natural raw materials.
Products selected for testing in patients with diabetes due to the possibility of its positive effects on different types of metabolism of the body and improve the trophic tissue. Thus, a set of phosphatides comprising the complex (phosphatidylcholine, phosphatidylserine, lecithin) and carnitine favorably affect lipid metabolism. Essential amino acids (methionine, tyrosine, phenylalanine, glutamic acid), enzymes DNKza / RNKza, dimetilaminesteraza, minerals (calcium and magnesium), a complex of B vitamins (B1, B3, B5, WB, B12), folic acid - the active members of the protein, water and salt, lipid, and primary exchanges. Extract of Ginkgo biloba and other herbal constituents, according to published sources (Michel PF Le doyen des ardes: Ie gingo biloba.Press Med., 1986 and others), a beneficial effect on the state of the vascular wall, blood rheology. Conducted numerous studies indicate a variety of therapeutic properties of a standard 24% of extract of Ginkgo biloba, namely: improving the content macroergs in various tissues (brain cells, muscle tissue, the cells of parenchymatous organs, etc.), the stabilization of the ionic potential of cell membranes, decrease in activity FSK (clotting factors) for up to two hours, the improvement of the biosynthesis of prostaglandins, the expression "antiradical" properties.
Clinical studies indicate that after administration of drugs containing a standardized extract of Ginkgo biloba extract increases the synthesis of dopamine, biologically active substances of the extract promotes the release of catecholamines (epinephrine and norepinephrine), which has a positive effect on the function of catecholaminergic systems of the body (endocrine, cardiovascular, nervous) .
Some examples of clinical observations:
Patient M., aged 49. Diagnosis: DM of the first type, moderate, circulatory and dismetabolic encephalopathy. Diabetic neuropathy and angiopathy of the lower extremities. Suffers from diabetes for 10 years. If you receive a complaint of pain in the calf muscles, intermittent claudication by 100-200 meters, cramps in the calf muscles (especially at night), paresthesia, numbness, pain, excessive coldness in the feet, the noise in my head, headache, dizziness, incoordination of movements . When viewed from the foot pale, cold to the touch, hair is absent, pulsation vessels stop abruptly weakened. Prothrombin index (PTI) - 105%.
Received MEMORIA RICE for a month by increasing the scheme, starting with 1 / 2 to 2 tablets per day.
When re-examination of a clear positive trend. Intermittent claudication by 300-500 meters, there is a significant decrease in pain when walking, loss of sense of crawling and chilly feet, headaches, and the noise it does not bother to have improved vision. From the words of the patient, such a positive effect, he did not get from any drug. Objective status: feet warm to the touch, skin stop normal color, pulsation in the arteries satisfactory to both parties, PTI - 85%.
Patient S., aged 57. Diagnosis: the first type of diabetes, severe, diabetic angiopathy of lower extremities. Diabetic foot, neuropathic form. Ill for 27 years, disabled the second group. Complaints of numbness of the toes, increased chilly feet, pain in the calf muscles, intermittent claudication in 50-100 meters. Objective status: the right foot and 1 / 3 tibia hyperpigmented, edematous, cyanotic. On the back surface of the right foot ulcer-necrotic defects up to 2 cm, the edges of the ulcer swollen, poor sukrovichnoe discharge from the wound. PB - 103%.
Received supplements MEMORY RISE: 1 tablet 2 times a day, dressings. Inspection in a month: pain, numbness of toes does not bother, there may be no rest to 300-350 meters, ulcerative defect decreased to 0.2 cm, and a good edge epithelization, no discharge, granulation in the wound, bright, juicy, PB-79%.
Patient K., aged 69. Diagnosis: DM of the second type, insulinopotrebny, a severe form. Diabetic angiopathy of lower extremities. Diabetic foot, neuropathic form, gangrene of the first toe of left foot. DM patients for 16 years, disabled the second group. In history: 09/10/1998 - disarticulation of the first toe left foot, 03/11/1998 - resection of the first metatarsal bone without surgical wound. Complaints of pain in the feet and the pain intensifies during the motion, the phantom pain.
Objective status: both legs swollen, hyperpigmented, swelling of the left leg and foot, festering wound of the stump of the first metatarsal bone, putrid smell from the wound. Ripple on the arteries of the stop is not defined, hyperkeratosis toes, PTI - 99%.
MEMORY RISE appointed to 2 pills a day, while antibiotic therapy, bandaging ambulatory within 1-2 days. Control examination after five weeks: PTI - 80%, walking independently, melosalgia recently little worried, visible swelling on the lower limbs there, the skin of normal coloration, pigmentation not, the wound healed by secondary intention, and the steps to the touch still cold, but the pulsation of the arteries to stop determined, although it weakened.
Thus, we can draw the following conclusions:
1. Acceptance of biologically active food supplement company ART LIFE MEMORY RISE helps:
- The normalization of the blood coagulation system;
- Reduce swelling and pain;
- Improve tissue regeneration;
- Improve blood flow in the vessels of the lower extremities.
2. The effective dose of SBC is to
2 tablets per day.
3. BAA MEMORY RISE well tolerated by patients.
4. BAD ART LIFE MEMORY RISE can be effectively used in the treatment of diabetes as an aid, as well as for the prevention of vascular complications.