K.YU, Bezrukov, State Medical Academy, Chita
The problem of therapy of acute pneumonia in children are most relevant in today's Pediatrics.
In the present work was to study the clinical effects of biologically active food supplement PULMOKLINZ (production company ARTLIFE) in acute pneumonia in children of preschool and primary school age who are hospitalized. Diagnosed on the basis of clinical, laboratory and instrumental examination with mandatory radiographic confirmation. All under the supervision of children consisted of 78 patients, 32 of which in addition to conventional therapy (antibiotic, symptomatic, physiotherapy) received PULMOKLINZ 1 tablet 3 times daily for 10 days.
The control group consisted of 46 children who received only conventional therapy. Patients comparison groups were not significant differences by gender, age, severity of disease.
As shown by clinical studies in acute pneumonia in patients receiving additional therapy in PULMOKLINZ, quickly normalize the febrile reaction, disappeared intoxication symptoms, local changes in the form of wheezing in the lungs occurs the elimination of foci in X-ray examination.
But the most significant effect of the drug was noted on the nature of cough, which since the early days became softer and better clearing his throat, and pain in the lungs, eliminating the first-second day of dietary supplements. Moreover, the improvement noted in both uncomplicated and complicated forms of the disease.
Previously it was shown that in acute pneumonia in children vary considerably processes of antioxidant defense and lipid peroxidation in the lymphocytes, which contributes to damage of cell membranes. Violation of membrane interactions provokes not only decrease the nonspecific defense factors, but also the failure of the immune response.
Use in the treatment of PULMOKLINZ led to activation of the enzymatic antioxidant defenses. After treatment the product core activity of antioxidant enzymes - superoxide dismutase - increased significantly, reaching almost the level of healthy children.
The use of dietary supplements also increase the functional activity of blood lymphocytes by NBT-test.
The use of dietary supplements ARTLIFE PULMOKLINZ reduces antibacterial treatment, reduces the length of hospitalization of patients.