The peculiarity of the oral cavity is that, firstly, with it there are two vital functions of the human body - breathing and feeding, and, secondly, that it is constantly in contact with the external environment.
The presence of such in the oral cavity are more different kinds of bacteria than in other parts of the gastrointestinal tract, and this amount, according to different authors, ranges from 160 to 300 species.
number of bacteria is due not only because they fall into the mouth with air, water, food - so-called transit microorganisms, length of stay are limited. This involves resident (permanent) microflora, forming a rather complex and stable ecosystem of the oral cavity. These are nearly 30 microbial species. Under normal conditions (do not use antiseptic creams, antibiotics, etc.) changes in the existing ecosystem occur, depending on time of day, year, etc., and only in one direction, ie, changing only the number of representatives of different microorganisms.
The composition of the microflora depends on salivation, texture and character of food, as well as the content of oral hygiene, condition of tissues and organs of the oral cavity and the presence of somatic diseases.
Disorders of salivation, chewing and swallowing always lead to an increase in the number of microorganisms in the oral cavity. Various anomalies and defects that hinder leaching microorganisms current saliva (caries etc.), help to increase their numbers in the oral cavity. They vigorously proliferate in unhygienic content of the oral cavity.
The normal microflora of the mouth rather resistant to the action of antibacterial factors of oral fluid. However, it performs the function of «biological barrier», preventing the proliferation of pathogens originating from the external environment. Microflora also participates in the cleaning of the mouth, is a constant stimulus for local immunity. Antibacterial activity of saliva and the number of species in the oral cavity microorganisms in a state of dynamic equilibrium. The main function of antibacterial system in saliva is not complete suppression of the microflora in the oral cavity, and in controlling the quantity and quality of its composition.
It follows from the facts of dental caries and inflammatory diseases of the oral cavity arise when disturbed the normal balance between own and alien microflora.
Therefore, funds for hygiene with antibacterial components should be aimed at maintaining the constancy of the microflora on the physiological level, ie, when there is no shift of quantitative and qualitative composition of microorganisms in favor of the pathogen throughout the period of vital activity.
It is from these positions ArtLife Company has developed a new medical-prophylactic toothpaste N-Zim Prebio. It has no analogues on the dental market, and its unique structure is designed taking into account the normal microflora of the oral cavity.
Thanks to special components, which is part of N-Zim Prebio normal acid-alkaline balance in the oral cavity. Reduces sensitivity and bleeding gums, reduced the symptoms in inflammatory processes. In addition, the toothpaste has antiviral and anti-inflammatory effect, and also protects against the formation of harmful bacteria, keeping the useful microflora and maintaining perfect oral hygiene.
Distinctive feature of the N-Zim Prebio is used in the recipe lysate lactobacilli. It prevents the proliferation of pathogens in the oral cavity, enhances the local immune system, protects teeth from cavities and plaque formation. And in combination with aloe vera extract provides wound-healing effect on the mucous membrane of the mouth and gums.
The plant enzyme papain effectively splits the dangerous plaque, and does so carefully, that does not cause any damage to tooth enamel, and nano-particles of silica adsorbed its output at the rinsing. This allows for a long time to maintain a sense of purity and freshness in the mouth.
Application of N-Zim Prebio will have a therapeutic effect and provide a reliable prevention of diseases of hard tissues of teeth and soft tissues of the oral cavity.